Search AccessScience
Browse Topics

Search Results: Aging (genetics)

Aging is a complex, multifactorial process that is influenced by both genes and the environment. Aging occurs in almost all animals and is a major...



= Encyclopedia Article; = Research Update
Figure 1.Survival curve for a typical Caenorhabditis elegans longevity mutant. Life span is determined in C. elegans by following the survival of a cohort of approximately 100 worms that are synchronously aging. The normal mean life span of C. elegans is 20 days, whereas the long-lived mutants have a mean life span of 36 days.
From update 'Aging (genetics)'
Figure 2.Factors affecting aging. Aging may be due to the accumulation of molecular damage resulting from the action of reactive oxygen radicals. Evidence for this mechanism comes from genetic alterations that increase the levels of antioxidant enzymes and appear to promote longevity. Molecular chaperones also promote longevity, by restoring damaged proteins to their healthy folded state.
From update 'Aging (genetics)'